By Leon V. Berhardt
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Additional resources for Advances in Medicine and Biology, Volume 20
For more information of rapid troponin testing, readers are referred to the recent reports [31-35]. The device utilized nonmagnetic particles to isolate cardiac markers from whole blood thereafter labeling these cardiac markers with a glucose molecule to allow for a glucometer to measure the concentration of the Troponin cardiac marker in the sample. Blood glucose concentration was measured by glucose oxidase-peroxidase system. In this system, the reagent strips contained test area, which was impregnated with enzyme and two metal electrodes.
The MALDI mass spectrometry technique showed potential of exploring AMI sensitive Troponins with other possible proteins. The concentration of troponinT in blood sample was correlated with proportional concentration of glucose measured by pencil miniature glucometer. Conclusion: The magnetic immunoassay of point-of-care method shows potential as rapid reliable cost-effective and efficient as cardiac protection device. The technique is simple, user friendly and cost-effective. The nanotechnology based glucometer may provide portable miniature point-of-care testing at low cost.
2007 May;20(3):360-5. Säring D, Ehrhardt J, Stork A, Bansmann MP, Lund GK, Handels H. Computer-assisted analysis of 4D cardiac MR image Methods Inf. Med. 2006;45(4):377-83. Lorenzo-Valdés M, Sanchez-Ortiz GI, Elkington AG, Mohiaddin RH, Rueckert D. Segmentation of 4D cardiac MR images Med. Image Anal. 2004; 8(3):255-65. Troponin T: A Search of Superparamagnetic Iron-Oxide bound Antitroponin… 17  Sharma R, Haik Y, Chen CJ. Superparamagnetic iron oxide-myoglobin as potential nanoparticle: Iron Oxide magnetic resonance imaging marker in mouse imaging.
Advances in Medicine and Biology, Volume 20 by Leon V. Berhardt