By Reza Ardehali, Marco Perez, Paul Wang
Written, reviewed, and edited in a collaborative attempt through cardiology fellows and school of 1 of the main prestigious educational facilities within the nation, this concise quantity provides cardiology fellows the publication they've got lengthy needed. Keeping assurance of the underlying pathophysiology and mechanism of sickness to a minimal, the authors concentrate on the prognosis and remedy of cardiac problems. sensible and simply available on the time of selection making, the booklet relays very important ideas via concise and to-the-point pearls and by using set of rules charts and illustrations.
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Additional resources for A Practical Approach to Cardiovascular Medicine
Work-Up It is important to assess for the presence of hypertensive urgency or emergency. If present, proceed to immediate therapy as outlined below. Assess for major cardiovascular risk factors: • HTN • Smoking • Body mass index (BMI) >30 • Dyslipidemia • Diabetes mellitus • Chronic kidney disease • Age (>55 in men; >65 in woman) • Family history of premature cardiovascular disease (men <55 years; women <65 years). Assess for chronic end-organ damage: • Left ventricular hypertrophy (LVH), angina, or prior MI, CHF • Stroke, transient ischemic attack, intracranial hemorrhage • Chronic kidney disease (reduced eGFR or elevated albumin excretion) • Peripheral vascular disease • Retinopathy.
EV I DE NC E - B ASE D P R AC T I C E Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) Context: Assess whether beta-blockers are useful in preventing cardiovascular events as compared to CCBs. Goal: To compare whether atenolol or amlodipine is more effective in preventing fatal and nonfatal CVD events. Method: Multicenter RCT involving 19 257 participants 40–79 years of age with HTN and ≥3 other CHD risk factors were assigned to either amlodipine (with ACE-I as required) versus atenolol (with thiazide as required).
Method: Multicenter RCT involving 11 506 participants with HTN and high cardiovascular risk. The primary endpoint was the composite of death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, hospitalization for angina, resuscitation after sudden cardiac arrest, and coronary revascularization. Results: Study stopped prematurely after a mean follow-up of 36 months. Though BP goals were reached in both arms equally, the combination of benazepril–amlodipine was superior to benazepril–hydrochlorothiazide in terms of primary endpoint.
A Practical Approach to Cardiovascular Medicine by Reza Ardehali, Marco Perez, Paul Wang