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With other parameters fi xed, a 1-mm slice will acquire one eighth as many photons as an 8-mm slice. The noise in the 1-mm slice will be the square root of 8 higher than the noise of the thick slice, according to the laws of Poisson statistics. Thus, thinner slices will almost always require higher dose scanning and will be noisier than the thicker-slice alternatives. 35 mm is available, which is 23 times less than 8 mm. In screening studies such as cardiac screening, lung screening, or virtual colonography, thicker slices are preferred to minimize radiation exposure to a healthy patient.

Sugawara Y, Zasadny KR, Neuhoff AW, Wahl RL. Reevaluation of the standardized uptake value for FDG: variations with body weight and methods for correction. Radiology. 1999;213:521–525. 13. Watson CC. New faster, image-based scatter correction for 3D PET. IEEE Trans Nucl Sci. 2000;47:1587–1594. 14. Zaidi H, Koral KF. Scatter modelling and compensation in emission tomography. Eur J Nucl Med Mol Imaging. 2004;31:761–782. 18 Part I Instrumentation and Principles of Imaging 15. Defrise M, Kinahan PE, Townsend DW, Michel C, Sibomana M, Newport DF.

21 References 1. Takahashi S. Rotational Radiography. Tokyo: Japan Society for the Promotion of Science; 1957. 2. Cormack A. Representation of function by its line integrals with some radiological applications. Part I. J Appl Phys. 1964;35:2722. 3. Cormack A. Representation of function by its line integrals with some radiological applications. Part II. J Appl Phys. 1964;35:2908. 4. Oldendorf WH. Isolated flying spot detection of radiodensity discontinuities—displaying the internal structural pattern of a complex object.

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